Product | Conc. Provided | Comments | Cat. No. |
| InSolution™ Bay 11-7082 | 100 mM
in DMSO | A selective and irreversible inhibitor of TNF-a-inducible phosphorylation of IkBa (IC50 = 10 mM). | |
InSolution™ IKK-2
Inhibitor IV | 10 mM
in DMSO | A cell-permeable, potent inhibitor of IKK-2 (IC50 = 18 nM). | |
| InSolution™ IKK-2 Inhibitor, SC-514 | 25 mM
in DMSO | A cell-permeable, potent, reversible, ATP competitive, selective inhibitor of IKK-2 (IC50 ~3-12 mM for IKK-2 homodimer, IKK-1/IKK-2 heterodimer, and IKK-2). | |
InSolution™ NF-kB
Activation Inhibitor | 10 mM
in DMSO | A cell-permeable, highly potent inhibitor of NF-kB transcriptional activation (IC50 = 11 nM in Jurkat cells) and LPS-induced TNF-a production (IC50 = 7 nM in murine splenocytes). | |
InSolution Inhibitors by Research Area 