4′-Epidoxorubicin, HCl

Orange-red solid. PROTECT FROM LIGHT. HYGROSCOPIC. A cell-permeable antitumor antibiotic. A stereoisomer of Doxorubicin (Cat. No. 324380) that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II. Purity: ≥95% by HPLC. RTECS QI9295750, CAS 56390-09-1.

Merck Index: 14, 3623
Ref.: Luck, H.J., et al. 1996. Semin. Oncol. 23, 33. Sandri, M.I., et al. 1996. Br. J. Cancer 73, 1518. Boddy, A.V., et al. 1995. Eur. J. Cancer 31A, 69. Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol. 35, 257.
R: 20/21/22-40; S: 22-36